The South African Menopause Society (SAMS) Statement on Compounded (Bioidentical) Menopausal Hormone Therapy, 18 October, 2023

SAMS CMHT guidelines final October 202

This statement from the South African Menopause Society (SAMS) is written as an advisory for healthcare practitioners due to concerns about the widespread use of unregulated compounded bioidentical hormone therapy (CBHT). Since CBHT is unregulated, there is ongoing anxiety about the quality, purity, potency, efficacy, sterility and safety of these products. Because the word ‘bioidentical’ is not a scientific term, but one used in
marketing to identify CBHT, the consensus for this statement was to use the words ‘compounded menopausal hormone therapy’ (CMHT) to describe this unregulated treatment, and the accepted global terminology ‘menopausal hormone therapy’(MHT) to denote a hormone treatment that has been approved and regulated by government agencies.

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